Surface representation of Ubiquitin.
Microscopy of a cell with neurofibrillary tangles (marked by arrows).
The ubiquitylation system (showing a RING E3 ligase).
Diagram of how microtubules disintegrate with Alzheimer's disease
Diagram of lysine 48-linked diubiquitin. The linkage between the two ubiquitin chains is shown in orange.
Overview of RNA interference.
Diagram of lysine 63-linked diubiquitin. The linkage between the two ubiquitin chains is shown in orange.

Three different maturation states of NFT have been defined using anti-tau and anti-ubiquitin immunostaining.

- Neurofibrillary tangle

Neurofibrillary tangles in Alzheimer's disease

- Ubiquitin
Surface representation of Ubiquitin.

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