A report on Nimetazepam

Intermediate-acting hypnotic drug which is a benzodiazepine derivative.

- Nimetazepam

5 related topics with Alpha

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A box of Mogadon pills containing 5mg of Nitrazepam.

Nitrazepam

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Hypnotic drug of the benzodiazepine class used for short-term relief from severe, disabling anxiety and insomnia.

Hypnotic drug of the benzodiazepine class used for short-term relief from severe, disabling anxiety and insomnia.

A box of Mogadon pills containing 5mg of Nitrazepam.
Nitrazepam synthesis:

Nitrobenzodiazepines such as nitrazepam, nimetazepam, flunitrazepam, and clonazepam are more toxic to the liver than other benzodiazepines as they are metabolically activated by CYP3A4 which can result in cytotoxicity.

Structural formula of benzodiazepines.

Benzodiazepine

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Fusion of a benzene ring and a diazepine ring.

Fusion of a benzene ring and a diazepine ring.

Structural formula of benzodiazepines.
Midazolam 1 & 5 mg/mL injections (Canada)
Temazepam (Normison) 10 mg tablets
Addiction experts in psychiatry, chemistry, pharmacology, forensic science, epidemiology, and the police and legal services engaged in delphic analysis regarding 20 popular recreational drugs. Benzodiazepines were ranked in this graph 7th in dependence, physical harm, and social harm.
Diazepam 2 mg and 5 mg diazepam tablets, which are commonly used in the treatment of benzodiazepine withdrawal.
Chlordiazepoxide 5 mg capsules, which are sometimes used as an alternative to diazepam for benzodiazepine withdrawal. Like diazepam it has a long elimination half-life and long-acting active metabolites.
Schematic diagram of the (α1)2(β2)2(γ2) GABAA receptor complex that depicts the five-protein subunits that form the receptor, the chloride (Cl−) ion channel pore at the center, the two GABA active binding sites at the α1 and β2 interfaces and the benzodiazepine (BZD) allosteric binding site at the α1 and γ2 interface.
Left: The 1,4-benzodiazepine ring system. Right: 5-phenyl-1H-benzo[e] [1,4]diazepin-2(3H)-one forms the skeleton of many of the most common benzodiazepine pharmaceuticals, such as diazepam (7-chloro-1-methyl substituted).
A pharmacophore model of the benzodiazepine binding site on the GABAA receptor. White sticks represent the carbon atoms of the benzodiazepine diazepam, while green represents carbon atoms of the nonbenzodiazepine CGS-9896. Red and blue sticks are oxygen and nitrogen atoms that are present in both structures. The red spheres labeled H1 and H2/A3 are, respectively, hydrogen bond donating and accepting sites in the receptor, while L1, L2, and L3 denote lipophilic binding sites.
The molecular structure of chlordiazepoxide, the first benzodiazepine. It was marketed by Hoffmann–La Roche from 1960 branded as Librium.
Xanax (alprazolam) 2 mg tri-score tablets

clonazepam, flunitrazepam, nimetazepam, nitrazepam

Carbamazepine

Anticonvulsant

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Anticonvulsants (also known as antiepileptic drugs or recently as antiseizure drugs) are a diverse group of pharmacological agents used in the treatment of epileptic seizures.

Anticonvulsants (also known as antiepileptic drugs or recently as antiseizure drugs) are a diverse group of pharmacological agents used in the treatment of epileptic seizures.

Carbamazepine

Nitrazepam, temazepam, and especially nimetazepam are powerful anticonvulsant agents, however their use is rare due to an increased incidence of side effects and strong sedative and motor-impairing properties.

MDMA (Ecstasy) pills. The Convention allows only government-approved medical and scientific uses of this and other substances.

Convention on Psychotropic Substances

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United Nations treaty designed to control psychoactive drugs such as amphetamine-type stimulants, barbiturates, benzodiazepines, and psychedelics signed in Vienna, Austria on 21 February 1971.

United Nations treaty designed to control psychoactive drugs such as amphetamine-type stimulants, barbiturates, benzodiazepines, and psychedelics signed in Vienna, Austria on 21 February 1971.

MDMA (Ecstasy) pills. The Convention allows only government-approved medical and scientific uses of this and other substances.
Despite its well-known presence in the rave scene, ketamine remains uncontrolled internationally due to its importance as an anesthetic in veterinary medicine.
Article 32 makes an exception for peyote and other wild psychotropic plants, to protect use in religious rituals in case such plants themselves were in the future added to Schedule I.
Psilocybin mushrooms are not controlled by the Convention, but the drugs contained in them are.
LSD and equipment used in its manufacture are subject to seizure under Article 22.
Crystal meth has emerged as a commonly abused drug, from the American and European rave scenes to East Asia.

nimetazepam

The Singapore embarkation card contains a warning to visitors about the death penalty for drug trafficking. Warning signs can be found at the Johor-Singapore Causeway and other border entries. Singapore Airlines and Jetstar Asia Airways also announce similar warnings to air passengers during flights to the country.

Misuse of Drugs Act (Singapore)

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Drug control law in Singapore classifying substances into three categories, Classes A, B, and C. Section 44 provides that "The Minister may, by an order published in the Gazette" add, remove, or transfer drugs among the classes.

Drug control law in Singapore classifying substances into three categories, Classes A, B, and C. Section 44 provides that "The Minister may, by an order published in the Gazette" add, remove, or transfer drugs among the classes.

The Singapore embarkation card contains a warning to visitors about the death penalty for drug trafficking. Warning signs can be found at the Johor-Singapore Causeway and other border entries. Singapore Airlines and Jetstar Asia Airways also announce similar warnings to air passengers during flights to the country.

Nimetazepam