Nonsteroidal anti-inflammatory drug

NSAIDNSAIDsnon-steroidal anti-inflammatory drugnonsteroidal anti-inflammatory drugsnon-steroidal anti-inflammatory drugsanti-inflammatory drugsanti-inflammatorynonsteroidal anti-inflammatory drugs (NSAIDs)non-steroidal anti-inflammatory agentsnon-steroidal anti-inflammatories
Nonsteroidal anti-inflammatory drugs (NSAIDs) are members of a drug class that reduces pain, decreases fever, prevents blood clots, and in higher doses, decreases inflammation.wikipedia
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Analgesic

analgesiaanalgesicspainkillers
Nonsteroidal anti-inflammatory drugs (NSAIDs) are members of a drug class that reduces pain, decreases fever, prevents blood clots, and in higher doses, decreases inflammation.
Analgesics include paracetamol (known in North America as acetaminophen or simply APAP), the nonsteroidal anti-inflammatory drugs (NSAIDs) such as the salicylates, and opioid drugs such as morphine and oxycodone.

Anti-inflammatory

antiinflammatoryanti-inflammatoriesanti-inflammatory drug
Nonsteroidal anti-inflammatory drugs (NSAIDs) are members of a drug class that reduces pain, decreases fever, prevents blood clots, and in higher doses, decreases inflammation.
Nonsteroidal anti-inflammatory drugs (NSAIDs) alleviate pain by counteracting the cyclooxygenase (COX) enzyme.

COX-2 inhibitor

COX-2 selective inhibitorCOX-2 inhibitorsCOX inhibitor
There are two types of NSAIDs available: non-selective and COX-2 selective.
Selective COX-2 inhibitors are a type of nonsteroidal anti-inflammatory drug (NSAID) that directly targets cyclooxygenase-2, COX-2, an enzyme responsible for inflammation and pain.

Ibuprofen

AdvilMotrinBrufen
The most prominent NSAIDs are aspirin, ibuprofen, and naproxen, all available over the counter (OTC) in most countries. Indomethacin, ketoprofen and piroxicam use appear to lead to the highest rate of gastric adverse effects, while ibuprofen (lower doses) and diclofenac appear to have lower rates.
Ibuprofen is a medication in the nonsteroidal anti-inflammatory drug (NSAID) class that is used for treating pain, fever, and inflammation.

Naproxen

Alevenaproxen sodiumAnaprox
The most prominent NSAIDs are aspirin, ibuprofen, and naproxen, all available over the counter (OTC) in most countries.
Naproxen, sold under the brand name Naprosyn among others, is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain, menstrual cramps, inflammatory diseases such as rheumatoid arthritis, and fever.

Prostaglandin-endoperoxide synthase 2

COX-2cyclooxygenase 2cyclooxygenase-2
NSAIDs work by inhibiting the activity of cyclooxygenase enzymes (COX-1 and/or COX-2).
PGHSs are targets for NSAIDs and PTGS2 (COX-2) specific inhibitors called coxibs.

Antipyretic

febrifugeantipyreticsanti-pyretic
Nonsteroidal anti-inflammatory drugs (NSAIDs) are members of a drug class that reduces pain, decreases fever, prevents blood clots, and in higher doses, decreases inflammation.
The most common antipyretics in the United States are ibuprofen and aspirin, which are nonsteroidal anti-inflammatory drugs (NSAIDs) used primarily as analgesics (pain relievers), but which also have antipyretic properties; and acetaminophen (paracetamol), an analgesic with weak anti-inflammatory properties.

Rheumatoid arthritis

rheumatoidrheumatic arthritisarthritis, rheumatoid
Use of methotrexate together with NSAIDS in rheumatoid arthritis is safe, if adequate monitoring is done.
Pain medications, steroids, and NSAIDs are frequently used to help with symptoms.

Low back pain

lumbagolower back painlower back
NSAIDs are recommended if these are not sufficiently effective.

Paracetamol

acetaminophenPanadolTylenol PM
Paracetamol (acetaminophen) is generally not considered an NSAID because it has only minor anti-inflammatory activity.
Paracetamol has relatively little anti-inflammatory activity, unlike other common analgesics such as the nonsteroidal anti-inflammatory drugs (NSAIDs) aspirin, and ibuprofen, but ibuprofen and paracetamol have similar effects in the treatment of headache.

Osteoarthritis

arthrosisdegenerative joint diseaseKnee osteoarthritis
Pain medications may include paracetamol (acetaminophen) as well as NSAIDs such as naproxen or ibuprofen.

Cyclooxygenase

COXcyclooxygenase 1cyclo-oxygenase
NSAIDs work by inhibiting the activity of cyclooxygenase enzymes (COX-1 and/or COX-2).
Nonsteroidal anti-inflammatory drugs (NSAIDs), such as aspirin and ibuprofen, exert their effects through inhibition of COX.

Gout

gouty arthritispodagragout attack
NSAIDs are also used in the acute pain caused by gout because they inhibit urate crystal phagocytosis besides inhibition of prostaglandin synthase.
Treatment with nonsteroidal anti-inflammatory drugs (NSAIDs), steroids, or colchicine improves symptoms.

Ankylosing spondylitis

Bekhterev’s DiseaseBekhterev's Diseasespondylitis, ankylosing
Medications used include NSAIDs, steroids, DMARDs such as sulfasalazine, and biologic agents such as infliximab.

NSAID hypersensitivity reactions

A variety of allergic or allergic-like NSAID hypersensitivity reactions follow the ingestion of NSAIDs.
NSAID or nonsteroidal anti-inflammatory drug hypersensitivity reactions encompasses a broad range of allergic or allergic-like symptoms that occur within minutes to hours after ingesting aspirin or other NSAID nonsteroidal anti-inflammatory drugs.

Tennis elbow

lateral epicondylitisHumeral EpicondyleLateral Epicondylalgia
Pain medications such as NSAIDS or acetaminophen may be used.

Dysmenorrhea

dysmenorrhoeamenstrual crampspainful menstruation
Medications that may help include NSAIDs such as ibuprofen, hormonal birth control and the IUD with progestogen.

Patent ductus arteriosus

ductus arteriosusductus arteriosus, patentAdult patent ductus arteriosus
In a more specific application, the reduction in prostaglandins is used to close a patent ductus arteriosus in neonates if it has not done so physiologically after 24 hours.
In these cases, prostaglandins are used to keep the PDA open, and NSAID s are not administered until surgical correction of the two defects is completed.

Rofecoxib

VioxxVioxx (Rofecoxib)
Rofecoxib (Vioxx) was shown to produce significantly fewer gastrointestinal adverse drug reactions (ADRs) compared with naproxen.
Rofecoxib is a COX-2 selective nonsteroidal anti-inflammatory drug (NSAID).

Aspirin exacerbated respiratory disease

aspirin-induced asthmaSamter's triadAspirin-exacerbated respiratory disease
Symptoms, which develop immediately to hours after ingesting any of various NSAIDs that inhibit COX-1, are: 1) exacerbations of asthmatic and rhinitis (see aspirin-induced asthma) symptoms in individuals with a history of asthma or rhinitis and 2) exacerbation or first-time development of wheals or angioedema in individuals with or without a history of chronic urticarial lesions or angioedema.
Aspirin exacerbated respiratory disease (AERD), also termed aspirin-induced asthma, is a medical condition initially defined as consisting of three key features: asthma, respiratory symptoms exacerbated by aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs), and nasal polyps.

Indometacin

indomethacinIndo-LemmonIndocin
Indomethacin, ketoprofen and piroxicam use appear to lead to the highest rate of gastric adverse effects, while ibuprofen (lower doses) and diclofenac appear to have lower rates.
Indometacin, also known as indomethacin, is a nonsteroidal anti-inflammatory drug (NSAID) commonly used as a prescription medication to reduce fever, pain, stiffness, and swelling from inflammation.

Drug class

class of drugsclass of medicationsclasses of drugs
Nonsteroidal anti-inflammatory drugs (NSAIDs) are members of a drug class that reduces pain, decreases fever, prevents blood clots, and in higher doses, decreases inflammation.
The class of nonsteroidal anti-inflammatory drugs (NSAIDs) is one such example.

Diclofenac

diclofenac sodiumVoltarenCambia
Indomethacin, ketoprofen and piroxicam use appear to lead to the highest rate of gastric adverse effects, while ibuprofen (lower doses) and diclofenac appear to have lower rates.
Diclofenac, sold under the trade names Voltaren among others, is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain and inflammatory diseases such as gout.

Piroxicam

FeldeneFeldene (piroxicam)Pirohexal-D
Indomethacin, ketoprofen and piroxicam use appear to lead to the highest rate of gastric adverse effects, while ibuprofen (lower doses) and diclofenac appear to have lower rates.
Piroxicam is a nonsteroidal anti-inflammatory drug (NSAID) of the oxicam class used to relieve the symptoms of painful inflammatory conditions like arthritis.

Ketoprofen

ActronOrudisOruvail
Indomethacin, ketoprofen and piroxicam use appear to lead to the highest rate of gastric adverse effects, while ibuprofen (lower doses) and diclofenac appear to have lower rates.
Ketoprofen is one of the propionic acid class of nonsteroidal anti-inflammatory drugs (NSAID) with analgesic and antipyretic effects.