Opiate

opiatesOpiate drugOpiate pathwayopiumopiate alkaloidsopiate/opioidopioidopioid analgesics
Opiate is a term classically used in pharmacology to mean a drug derived from opium.wikipedia
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Opium

opium tradeopium addictionraw opium
Opiate is a term classically used in pharmacology to mean a drug derived from opium.
The latex also contains the closely related opiates codeine and thebaine, and non-analgesic alkaloids such as papaverine and noscapine.

Opioid

opioidsopioid-induced constipationopioid analgesic
Opioid, a more modern term, is used to designate all substances, both natural and synthetic, that bind to opioid receptors in the brain (including antagonists).
Opioids include opiates, an older term that refers to such drugs derived from opium, including morphine itself.

Morphine

morphiamorphine addictionmorphine sulfate
The psychoactive compounds found in the opium plant include morphine, codeine, and thebaine. The major psychoactive opiates are morphine, codeine, and thebaine.
Morphine is a pain medication of the opiate family which is found naturally in a number of plants and animals.

Codeine

codeine phosphatecodeine hydrochlorideCod'ine
The psychoactive compounds found in the opium plant include morphine, codeine, and thebaine. The major psychoactive opiates are morphine, codeine, and thebaine.
Codeine is an opiate used to treat pain, coughing, and diarrhea.

Opioid receptor

opioid receptorsopioidopiate receptor
Opioid, a more modern term, is used to designate all substances, both natural and synthetic, that bind to opioid receptors in the brain (including antagonists).
By the mid-1960s, it had become apparent from pharmacologic studies that opiate drugs were likely to exert their actions at specific receptor sites, and that there were likely to be multiple such sites.

Thebaine

thebaïne
The psychoactive compounds found in the opium plant include morphine, codeine, and thebaine. The major psychoactive opiates are morphine, codeine, and thebaine.
Thebaine (paramorphine), also known as codeine methyl enol ether, is an opiate alkaloid, its name coming from the Greek Θῆβαι, Thēbai (Thebes), an ancient city in Upper Egypt.

Papaverine

Papaverine hydrochloride
Papaverine, noscapine, and approximately 24 other alkaloids are also present in opium but have little to no effect on the human central nervous system.
While it is found in the opium poppy, papaverine differs in both structure and pharmacological action from the analgesic (morphine-related) opium alkaloids (opiates).

Psychoactive drug

psychoactivepsychotropicdrug
The major psychoactive opiates are morphine, codeine, and thebaine.
This class of drugs can be highly addictive, and includes opiate narcotics, like morphine and codeine.

Papaver somniferum

opium poppyopium poppiespoppy
Opiates are alkaloid compounds naturally found in the opium poppy plant Papaver somniferum.
Opium contains a class of naturally occurring alkaloids known as opiates, that include morphine, thebaine, codeine, papaverine, noscapine and oripavine.

Dipropanoylmorphine

Nicomorphine (morphine dinicotinate), dipropanoylmorphine (morphine dipropionate), desomorphine (di-hydro-desoxy-morphine), methyldesorphine, acetylpropionylmorphine, dibenzoylmorphine, diacetyldihydromorphine, and several others are also derived from morphine.
Dipropanoylmorphine (Dipropionylmorphine in U.S. English) is an opiate derivative, the 3,6-dipropanoyl ester of morphine.

Acetylpropionylmorphine

Nicomorphine (morphine dinicotinate), dipropanoylmorphine (morphine dipropionate), desomorphine (di-hydro-desoxy-morphine), methyldesorphine, acetylpropionylmorphine, dibenzoylmorphine, diacetyldihydromorphine, and several others are also derived from morphine.
Acetylpropionylmorphine is an opiate analogue that is an ester of morphine.

Diacetyldihydromorphine

Dihydroheroindihydrodiacetylmorphine
Nicomorphine (morphine dinicotinate), dipropanoylmorphine (morphine dipropionate), desomorphine (di-hydro-desoxy-morphine), methyldesorphine, acetylpropionylmorphine, dibenzoylmorphine, diacetyldihydromorphine, and several others are also derived from morphine.
Diacetyldihydromorphine (also known as Paralaudin, dihydroheroin, acetylmorphinol or dihydroxycodeinon) is a potent opiate derivative developed in Germany in 1929 which is rarely used in some countries for the treatment of severe pain such as that caused by terminal cancer, as another form of diamorphine (also commonly known as Heroin).

Dibenzoylmorphine

Nicomorphine (morphine dinicotinate), dipropanoylmorphine (morphine dipropionate), desomorphine (di-hydro-desoxy-morphine), methyldesorphine, acetylpropionylmorphine, dibenzoylmorphine, diacetyldihydromorphine, and several others are also derived from morphine.
Dibenzoylmorphine is an opiate analogue that is a derivative of morphine.

Opioid epidemic

opioid crisis2018 opioid crisisa drug crisis in the city and surrounding county
Opioids are a diverse class of moderately strong painkillers, including oxycodone (commonly sold under the trade names OxyContin and Percocet), hydrocodone (Vicodin, Norco) and a very strong painkiller, fentanyl, which is synthesized to resemble other opiates such as opium-derived morphine and heroin.

Δ-opioid receptor

DORδ-opioiddelta opioid receptor
These receptors fall into 3 classes: μ (mu), δ (delta), and κ (kappa) receptors.
Opiates and opioids with δ activity mimic this effect.

Alkaloid

alkaloidspurine alkaloidalkaloid biosynthesis
Opiates are alkaloid compounds naturally found in the opium poppy plant Papaver somniferum.

Uniform Controlled Substances Act

Opiates are considered drugs with moderate to high abuse potential and are listed on various "Substance-Control Schedules" under the Uniform Controlled Substances Act of the United States of America.

World Health Organization

WHOWorld Health OrganisationWorld Health Organization (WHO)
In 2016, the World Health Organization reported that 27 million people suffer from opioid abuse disorder.

Benzylisoquinoline

1-BenzylisoquinolineBIA
Opiates belong to the large biosynthetic group of benzylisoquinoline alkaloids, and are so named because they are naturally occurring alkaloids found in the opium poppy.

Noscapine

narcotine
Papaverine, noscapine, and approximately 24 other alkaloids are also present in opium but have little to no effect on the human central nervous system.

Central nervous system

CNScentralcentral nervous system (CNS)
Papaverine, noscapine, and approximately 24 other alkaloids are also present in opium but have little to no effect on the human central nervous system.

Hydrocodone

TussionexHycodandihydrocodeinone
Very small quantities of hydrocodone and hydromorphone are detected in assays of opium on rare occasions; it appears to be produced by the plant under circumstances and by processes which are not understood at this time and may include the action of bacteria.

Hydromorphone

DilaudidPalladonedihydromorphinone
Very small quantities of hydrocodone and hydromorphone are detected in assays of opium on rare occasions; it appears to be produced by the plant under circumstances and by processes which are not understood at this time and may include the action of bacteria.

Dihydrocodeine

DF118dicodideDihydrocodeine bitartrate
Dihydrocodeine, oxymorphol, oxycodone, oxymorphone, metopon and possibly other derivatives of morphine and/or hydromorphone also are found in trace amounts in opium.

Oxymorphol

6α-oxymorphol
Dihydrocodeine, oxymorphol, oxycodone, oxymorphone, metopon and possibly other derivatives of morphine and/or hydromorphone also are found in trace amounts in opium.