Toxicity due to excessive consumption of opioids, such as morphine, codeine, heroin, fentanyl, tramadol, and methadone.- Opioid overdose
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Substance use disorder relating to the use of an opioid.
Complications may include opioid overdose, suicide, HIV/AIDS, hepatitis C, and problems at school, work, or home.
Opiate and prodrug of morphine used to treat pain, coughing, and diarrhea.
Care should be used during breastfeeding, as it may result in opiate toxicity in the baby.
Medication used to reverse the effects of opioids.
It is commonly used to counter decreased breathing in opioid overdose.
Compare hypopnea, bradypnea, and hyperventilation.
If the respiratory depression occurs from opioid overdose, usually an opioid antagonist, most likely naloxone, will be administered.
Opioids are substances that act on opioid receptors to produce morphine-like effects.
Other medical uses include suppression of diarrhea, replacement therapy for opioid use disorder, reversing opioid overdose, and suppressing cough.
Ingestion or application of a drug or other substance in quantities much greater than are recommended.
A person experiencing an opioid overdose might also have muscle spasms, seizures and decreased consciousness.
The μ-opioid receptors (MOR) are a class of opioid receptors with a high affinity for enkephalins and beta-endorphin, but a low affinity for dynorphins.
Fatal opioid overdose typically occurs due to bradypnea, hypoxemia, and decreased cardiac output (hypotension occurs due to vasodilation, and bradycardia further contributes to decreased cardiac output).
Opioid used as a recreational drug for its euphoric effects.
Heroin overdose is usually treated with the opioid antagonist, naloxone.
In the United States, prescription monitoring programs (PMPs) or prescription drug monitoring programs (PDMPs) are state-run programs which collect and distribute data about the prescription and dispensation of federally controlled substances and, depending on state requirements, other potentially abusable prescription drugs.
PMPs are meant to help prevent adverse drug-related events such as opioid overdoses, drug diversion, and substance abuse by decreasing the amount and/or frequency of opioid prescribing, and by identifying those patients who are obtaining prescriptions from multiple providers (i.e., "doctor shopping") or those physicians overprescribing opioids.
British racing driver, lawyer, and president of the Fédération Internationale de l'Automobile (FIA), a non-profit association which represents the interests of motoring organisations and car users worldwide.
At an inquest on 10 June 2009, the Westminster coroner declared that he had died due to non-dependent drug abuse.