Organic synthesis

synthesissynthesizedsyntheticsynthesizesynthesessynthesis of organic compoundsorganic synthesessynthetic organic chemistrysyntheticallychemical synthesis
Organic synthesis is a special branch of chemical synthesis and is concerned with the intentional construction of organic compounds.wikipedia
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Organic chemistry

organicorganic chemistorganic chemical
Organic molecules are often more complex than inorganic compounds, and their synthesis has developed into one of the most important branches of organic chemistry.
The study of organic reactions includes the chemical synthesis of natural products, drugs, and polymers, and study of individual organic molecules in the laboratory and via theoretical (in silico) study.

Chemical synthesis

syntheticsynthesissynthesized
Organic synthesis is a special branch of chemical synthesis and is concerned with the intentional construction of organic compounds. A total synthesis is the complete chemical synthesis of complex organic molecules from simple, commercially available (petrochemical) or natural precursors.
Organic synthesis is a special branch of chemical synthesis dealing with the synthesis of organic compounds.

Convergent synthesis

linear synthesisconvergenceconvergent
In a linear synthesis—often adequate for simple structures—several steps are performed one after another until the molecule is complete; the chemical compounds made in each step are called synthetic intermediates.
In chemistry a convergent synthesis is a strategy that aims to improve the efficiency of multistep synthesis, most often in organic synthesis.

Inorganic chemistry

inorganicinorganic chemistinorganic compounds
Organic molecules are often more complex than inorganic compounds, and their synthesis has developed into one of the most important branches of organic chemistry.
Soluble inorganic compounds are prepared using methods of organic synthesis.

Kinetic resolution

dynamic kinetic resolutionenzymatic resolutionhydrolytic kinetic resolution
In the later half of the twentieth century, chemists began to develop methods of stereoselective catalysis and kinetic resolution whereby reactions could be directed to produce only one enantiomer rather than a racemic mixture.
Kinetic resolution is a concept in organic chemistry and can be used for the preparation of chiral molecules in organic synthesis.

Robert Burns Woodward

Robert B. WoodwardR. B. WoodwardR.B. Woodward
Robert Burns Woodward, who received the 1965 Nobel Prize for Chemistry for several total syntheses (e.g., his 1954 synthesis of strychnine ), is regarded as the father of modern organic synthesis.
He is considered by many to be the preeminent organic chemist of the twentieth century, having made many key contributions to the subject, especially in the synthesis of complex natural products and the determination of their molecular structure.

Elias James Corey

E. J. CoreyElias J. CoreyE.J. Corey
Elias James Corey brought a more formal approach to synthesis design, based on retrosynthetic analysis, for which he won the Nobel Prize for Chemistry in 1990.
In 1990, he won the Nobel Prize in Chemistry "for his development of the theory and methodology of organic synthesis", specifically retrosynthetic analysis.

Retrosynthetic analysis

functional group interconversionretrosynthesisretrosynthetic
Elias James Corey brought a more formal approach to synthesis design, based on retrosynthetic analysis, for which he won the Nobel Prize for Chemistry in 1990.
Retrosynthetic analysis is a technique for solving problems in the planning of organic syntheses.

Hydrogenation

hydrogenatedcatalytic hydrogenationhydrogenated vegetable oil
Early examples include stereoselective hydrogenations (e.g., as reported by William Knowles and Ryōji Noyori, and functional group modifications such as the asymmetric epoxidation of Barry Sharpless; for these specific achievements, these workers were awarded the Nobel Prize in Chemistry in 2001.
In organic synthesis, transfer hydrogenation is useful for the asymmetric reduction of polar unsaturated substrates, such as ketones, aldehydes, and imines.

Electrosynthesis

electrochemicalTafel rearrangementelectrochemically
Electrosynthesis in chemistry is the synthesis of chemical compounds in an electrochemical cell.

Organic Syntheses

Org. Synth.Organic Syntheses, IncOrganic Synthesis
It publishes detailed and checked procedures for the synthesis of organic compounds.

Chiral resolution

resolvedresolving agentresolving
Historically, total syntheses targeted racemic mixtures, mixtures of both possible enantiomers, after which the racemic mixture might then be separated via chiral resolution.
One modern-day method of chiral resolution is used in the organic synthesis of the drug duloxetine:

Synthetic Reaction Updates

Methods in Organic SynthesisCatalysts and Catalysed Reactions
Methods in Organic Synthesis was an online database that was established in 1998 and updated weekly with the latest developments in organic synthesis.

Natural product

naturally occurringnatural productsnatural
Most complex natural products are chiral, and the bioactivity of chiral molecules varies with the enantiomer.
In addition, natural products are prepared by organic synthesis, and have played a central role to the development of the field of organic chemistry by providing tremendously challenging targets and problems for synthetic strategy and tactics.

Organic compound

syntheticorganicorganic compounds
Organic synthesis is a special branch of chemical synthesis and is concerned with the intentional construction of organic compounds. A total synthesis is the complete chemical synthesis of complex organic molecules from simple, commercially available (petrochemical) or natural precursors.

Total synthesis

total synthesesformal synthesissynthesis
There are several main areas of research within the general area of organic synthesis: total synthesis, semisynthesis, and methodology.

Semisynthesis

semi-syntheticsemisyntheticsemi-synthesis
There are several main areas of research within the general area of organic synthesis: total synthesis, semisynthesis, and methodology.

Methodology

methodologicalmethodologiesresearch methodology
There are several main areas of research within the general area of organic synthesis: total synthesis, semisynthesis, and methodology.

Molecule

molecularmoleculesmolecular structure
A total synthesis is the complete chemical synthesis of complex organic molecules from simple, commercially available (petrochemical) or natural precursors.

Petrochemical

petrochemicalspetroleum distillatepetro-chemical
A total synthesis is the complete chemical synthesis of complex organic molecules from simple, commercially available (petrochemical) or natural precursors.

Nature

naturalnatural worldmaterial world
A total synthesis is the complete chemical synthesis of complex organic molecules from simple, commercially available (petrochemical) or natural precursors.

List of Nobel laureates in Chemistry

Nobel laureate in ChemistryNobel laureateChemistry Nobel Laureate
Robert Burns Woodward, who received the 1965 Nobel Prize for Chemistry for several total syntheses (e.g., his 1954 synthesis of strychnine ), is regarded as the father of modern organic synthesis.

Strychnine

Strychnine sulfatestrychnine poisoningStrychnos nux vomica
Robert Burns Woodward, who received the 1965 Nobel Prize for Chemistry for several total syntheses (e.g., his 1954 synthesis of strychnine ), is regarded as the father of modern organic synthesis.

Wender Taxol total synthesis

WenderWender et al.
Some latter-day examples include Wender's, Holton's, Nicolaou's, and Danishefsky's total syntheses of the anti-cancer therapeutic, paclitaxel (trade name, Taxol).

Holton Taxol total synthesis

total synthesis of TaxolHoltonfirst article to be accepted for publication
Some latter-day examples include Wender's, Holton's, Nicolaou's, and Danishefsky's total syntheses of the anti-cancer therapeutic, paclitaxel (trade name, Taxol).