PCGEM1

Prostate-specific transcript 1 (non-protein coding), also known as PCGEM1, is a long non-coding RNA gene.wikipedia
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Long non-coding RNA

Long noncoding RNAlncRNAlncRNAs
Prostate-specific transcript 1 (non-protein coding), also known as PCGEM1, is a long non-coding RNA gene.
For example, in prostate tumours, PCGEM1 (one of two overexpressed ncRNAs) is correlated with increased proliferation and colony formation suggesting an involvement in regulating cell growth.

Gene

genesnumber of genesgene sequence
Prostate-specific transcript 1 (non-protein coding), also known as PCGEM1, is a long non-coding RNA gene.

Chromosome 2

2human chromosome 2Chromosome 2 (human)
In humans, it is located on chromosome 2q32.

Prostate cancer

prostatehormone-refractory prostate cancermetastatic prostate cancer
It is over-expressed in prostate cancer.

African Americans

African AmericanAfrican-Americanblack
In a study of prostate tumours from 88 men, levels of PCGEM1 were found to be higher in prostate cancer cells in African-American men than in Caucasian-American men.

White Americans

WhiteWhite AmericanCaucasian
In a study of prostate tumours from 88 men, levels of PCGEM1 were found to be higher in prostate cancer cells in African-American men than in Caucasian-American men.

Doxorubicin

adriamycinhydroxydaunorubicinDoxil
PCGEM1 inhibits doxorubicin-induced apoptosis of cells, via delayed induction of p53 and p21.

Apoptosis

apoptoticprogrammed cell deathcell death
PCGEM1 inhibits doxorubicin-induced apoptosis of cells, via delayed induction of p53 and p21.

P53

TP53p53 genep53 protein
PCGEM1 inhibits doxorubicin-induced apoptosis of cells, via delayed induction of p53 and p21.

P21

CDKN1Ap21Cip1WAF1
PCGEM1 inhibits doxorubicin-induced apoptosis of cells, via delayed induction of p53 and p21.