PTK2B

Pyk2Proline-rich tyrosine kinase (Pyk2, CADTK, PTK2beta)PTK2B/RAFTKPykPyk-2
Protein tyrosine kinase 2 beta is an enzyme that in humans is encoded by the PTK2B gene.wikipedia
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PTK2

focal adhesion kinaseFAKfocal adhesion kinase (FAK)
This protein has been shown to bind a CRK-associated substrate, a nephrocystin, a GTPase regulator associated with FAK, and the SH2 domain of GRB2.
The encoded protein is a member of the FAK subfamily of protein tyrosine kinases that included PYK2, but lacks significant sequence similarity to kinases from other subfamilies.

DDEF2

NPHP1

NPHP1 has been shown to interact with BCAR1, PTK2B, Filamin and INVS.

SORBS2

ArgBP2
In non-muscle cells, ArgBP2 bids Cbl which enhances the degradation of c-Abl; and also Pyk2 which promotes cytoskeletal remodeling.

Gelsolin

GSNGelsolinsGSN (gene)

RB1CC1

FIP200/RB1CC1
RB1CC1 has been shown to interact with PTK2B, ASK1 and PTK2.

PITPNM1

PITPNM1 has been shown to interact with PTK2B.

Tyrosine kinase

tyrosine kinasesprotein-tyrosine kinaseprotein tyrosine kinase
* Tyrosine kinase
PLK4; PTK2; PTK2B; PTK6; PTK7;

Enzyme

enzymologyenzymesenzymatic
Protein tyrosine kinase 2 beta is an enzyme that in humans is encoded by the PTK2B gene.

Gene

genesnumber of genesgene sequence
Protein tyrosine kinase 2 beta is an enzyme that in humans is encoded by the PTK2B gene.

Nicotinic acetylcholine receptor

nicotinic acetylcholine receptorsnicotinicnicotinic receptors
, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation.

Protein kinase C

PKCprotein kinase C (PKC)C
, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation.

Endothelium

endothelialendothelial cellsendothelial cell
In addition, SOCE-induced Pyk2 activation mediates disassembly of endothelial adherens junctions, via tyrosine (Y1981-residue) phosphorylation of VE-PTP.

Adherens junction

adherens junctionsZonula Adherensadheren
In addition, SOCE-induced Pyk2 activation mediates disassembly of endothelial adherens junctions, via tyrosine (Y1981-residue) phosphorylation of VE-PTP.

GRB2

Grb-2grb2 adaptor protein
This protein has been shown to bind a CRK-associated substrate, a nephrocystin, a GTPase regulator associated with FAK, and the SH2 domain of GRB2.