Papillary duct

Duct of Bellinipapillary ductsBellini's ductscollecting ducts of Bellinipapillary collecting ducts
Papillary (collecting) ducts are anatomical structures of the kidneys, previously known as the ducts of Bellini.wikipedia
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Lorenzo Bellini

Bellini
Papillary (collecting) ducts are anatomical structures of the kidneys, previously known as the ducts of Bellini.
At the age of twenty, when he had already begun his researches on the structure of the kidneys and had described the papillary ducts (also known as Bellini's ducts; latin: ductus Bellini, tubulus Bellini, tubuli Belliniani; see: duct of bellini, bellini duct carcinoma), as published in his book Exercitatio Anatomica de Structura Usu Renum (1662), he was chosen professor of theoretical medicine at Pisa, but soon after was transferred to the chair of anatomy.

Collecting duct system

collecting ductcortical collecting ductcollecting ducts
Papillary ducts represent the most distal portion of the collecting duct. Medullary collecting ducts converge to form a central (papillary) duct near the apex of eachrenal pyramid. They receive renal filtrate (precursor to urine) from several medullary collecting ducts and empty into a minor calyx. The simple columnar epithelium of the collecting duct system transitions into urothelium near the junction of a papillary duct and a minor calyx.

Renal medulla

renal papillamedullarenal pyramid
Medullary collecting ducts converge to form a central (papillary) duct near the apex of eachrenal pyramid.
Histologically it is marked by medullary collecting ducts converging to form a papillary duct to channel the fluid.

Kidney

kidneysrenalkidney disorder
Papillary (collecting) ducts are anatomical structures of the kidneys, previously known as the ducts of Bellini.

Renal physiology

tubular secretionhyperosmolalitykidney function
They receive renal filtrate (precursor to urine) from several medullary collecting ducts and empty into a minor calyx.

Urine

urinaryhuman urinepiss
They receive renal filtrate (precursor to urine) from several medullary collecting ducts and empty into a minor calyx.

Renal calyx

minor calyxrenal calycescalyces
They receive renal filtrate (precursor to urine) from several medullary collecting ducts and empty into a minor calyx.

Simple columnar epithelium

simple columnarciliated columnar epitheliumciliated simple columnar epithelium
The duct is lined by a layer of simple columnar epithelium resting on a thin basement membrane. The simple columnar epithelium of the collecting duct system transitions into urothelium near the junction of a papillary duct and a minor calyx.

Basement membrane

basement membranesbasement membrane zonecapillary basement membranes
The duct is lined by a layer of simple columnar epithelium resting on a thin basement membrane.

Transitional epithelium

urotheliumurothelialuroepithelial
The simple columnar epithelium of the collecting duct system transitions into urothelium near the junction of a papillary duct and a minor calyx.

Hormone

hormoneshormonalprohormone
These processes are mediated by hormones (aldosterone, vasopressin) and the osmolarity (concentration of electrically charged chemicals) of the surrounding medulla. Hormones regulate how permeable the papillary duct is to water and electrolytes.

Aldosterone

receptors, aldosteroneadrenoglomerulotropin
These processes are mediated by hormones (aldosterone, vasopressin) and the osmolarity (concentration of electrically charged chemicals) of the surrounding medulla.

Vasopressin

antidiuretic hormoneADHarginine vasopressin
These processes are mediated by hormones (aldosterone, vasopressin) and the osmolarity (concentration of electrically charged chemicals) of the surrounding medulla. In the medullary collecting duct specifically, vasopressin upregulates urea transporter A1.

Osmotic concentration

osmolaritymOsmhyperosmolarity
These processes are mediated by hormones (aldosterone, vasopressin) and the osmolarity (concentration of electrically charged chemicals) of the surrounding medulla.

Permeability (Earth sciences)

permeabilitypermeableimpermeable
Hormones regulate how permeable the papillary duct is to water and electrolytes.

Urea transporter

Urea Transporter A1urea transporter 4Urea transporter A2
In the medullary collecting duct specifically, vasopressin upregulates urea transporter A1.

Interstitium

cardiac interstitiuminterstitialinterstitial fluid
This increases the concentration of urea in the surrounding interstitium and increases the osmolarity.

Prostaglandin EP1 receptor

EP 1 PTGER1EP1
Studies in mice, rats, and guinea pigs have found EP 1 Messenger RNA and protein to be expressed in the papillary collecting ducts of the kidney, in the kidney, lung, stomach, thalamus, and in the dorsal root ganglia neurons as well as several central nervous system sites.

Collecting duct carcinoma

Bellini duct carcinomaCarcinoma of the Collecting Ducts of Bellini
Collecting duct carcinoma (CDC) is a type of kidney cancer that originates in the papillary duct of the kidney.

Supraoptic nucleus

supraopticsupraoptic (SON)SON
This chemical messenger travels via the bloodstream to its target cells in the papillary ducts in the kidneys, enhancing water reabsorption.

Loop of Henle

loops of HenleHenle’s loopnephron loop
By means of a countercurrent multiplier system, which uses electrolyte pumps, the loop of Henle creates an area of high urea concentration deep in the medulla, near the papillary duct in the collecting duct system.