Percutaneous umbilical cord blood sampling

Cordocentesispercutaneous umbilical blood sampling
For other uses see PUBS (disambiguation page)wikipedia
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Genetic testing

DNA testingDNA analysisDNA test
Percutaneous umbilical cord blood sampling (PUBS), also called cordocentesis, fetal blood sampling, or umbilical vein sampling is a diagnostic genetic test that examines blood from the fetal umbilical cord to detect fetal abnormalities.

Chorionic villus sampling

chorionic villi samplechorionic villi samplingchorionic villous sampling
PUBS provides a means of rapid chromosome analysis and is useful when information cannot be obtained through amniocentesis, chorionic villus sampling, or ultrasound (or if the results of these tests were inconclusive); this test carries a significant risk of complication and is typically reserved for pregnancies determined to be at high risk for genetic defect.
CVS usually takes place at 10–12 weeks' gestation, earlier than amniocentesis or percutaneous umbilical cord blood sampling.

Umbilical cord

umbilicalcord[umbilical] cord
Percutaneous umbilical cord blood sampling (PUBS), also called cordocentesis, fetal blood sampling, or umbilical vein sampling is a diagnostic genetic test that examines blood from the fetal umbilical cord to detect fetal abnormalities.
This diagnostic genetic test procedure is known as percutaneous umbilical cord blood sampling.

Amniocentesis

ACamnioamniotic centesis
PUBS provides a means of rapid chromosome analysis and is useful when information cannot be obtained through amniocentesis, chorionic villus sampling, or ultrasound (or if the results of these tests were inconclusive); this test carries a significant risk of complication and is typically reserved for pregnancies determined to be at high risk for genetic defect.

Prenatal testing

prenatal diagnosisprenatal screeningprenatal test
Valenti hypothesized in 1972 that the procedure he used to obtain fetal tissue could be used to obtain fetal blood, and in 1973, he was able to sample fetal vessels; fetoscopy was used and refined between 1974 and 1983 as a prenatal test to determine fetal status as well as obtain fetal blood and perform transfusions in some cases.

Purple urine bag syndrome

PUBS
For other uses see PUBS (disambiguation page)

Word-sense disambiguation

word sense disambiguationdisambiguationdisambiguate
For other uses see PUBS (disambiguation page)

Fetus

fetalfoetusfetuses
Percutaneous umbilical cord blood sampling (PUBS), also called cordocentesis, fetal blood sampling, or umbilical vein sampling is a diagnostic genetic test that examines blood from the fetal umbilical cord to detect fetal abnormalities.

In utero

unborn childuteroCryo Interactive
Fetal and maternal blood supply are typically connected in utero with one vein and two arteries to the fetus.

Umbilical vein

umbilicalumbilical veins[umbilical] veins
The umbilical vein is responsible for delivering oxygen rich blood to the fetus from the mother; the umbilical arteries are responsible for removing oxygen poor blood from the fetus.

Umbilical artery

umbilical arteriesarteria umbilicalisfetal hypogastric artery
The umbilical vein is responsible for delivering oxygen rich blood to the fetus from the mother; the umbilical arteries are responsible for removing oxygen poor blood from the fetus.

Perfusion

perfusedperfusetissue perfusion
This allows for the fetus’ tissues to properly perfuse.

Cytogenetics

cytogeneticcytogeneticistchromosome analysis
PUBS provides a means of rapid chromosome analysis and is useful when information cannot be obtained through amniocentesis, chorionic villus sampling, or ultrasound (or if the results of these tests were inconclusive); this test carries a significant risk of complication and is typically reserved for pregnancies determined to be at high risk for genetic defect.

Ultrasound

ultrasonicultrasonicsultrasounds
PUBS provides a means of rapid chromosome analysis and is useful when information cannot be obtained through amniocentesis, chorionic villus sampling, or ultrasound (or if the results of these tests were inconclusive); this test carries a significant risk of complication and is typically reserved for pregnancies determined to be at high risk for genetic defect.

Pregnancy

pregnantfirst trimesterpregnant women
PUBS provides a means of rapid chromosome analysis and is useful when information cannot be obtained through amniocentesis, chorionic villus sampling, or ultrasound (or if the results of these tests were inconclusive); this test carries a significant risk of complication and is typically reserved for pregnancies determined to be at high risk for genetic defect.

Genetic disorder

genetic diseasegenetic disordersgenetic diseases
PUBS provides a means of rapid chromosome analysis and is useful when information cannot be obtained through amniocentesis, chorionic villus sampling, or ultrasound (or if the results of these tests were inconclusive); this test carries a significant risk of complication and is typically reserved for pregnancies determined to be at high risk for genetic defect.

Immune thrombocytopenic purpura

idiopathic thrombocytopenic purpuraimmune thrombocytopeniaITP
It has been used with mothers with immune thrombocytopenic purpura.

Heredity

hereditaryinheritedinheritance
PUBS is a type of fetal blood sampling which was originally developed to determine the presence of hereditary abnormalities.

PH

pH levelneutralpH value
Currently, it can detect a number of abnormalities including pH levels, oxygen levels, chromosomal issues, and infections.

Uterus

wombuterineuteri
PUBS dates back to 1964 when Freda and Adamsons reported the removal of a uterus containing a fetus who had a buildup of fluid and ended up dying; however, this was one of the first procedures that showed promise for current day PUBS.

Fetoscopy

fetoscopesEmbryoscopyfetoscope
Valenti hypothesized in 1972 that the procedure he used to obtain fetal tissue could be used to obtain fetal blood, and in 1973, he was able to sample fetal vessels; fetoscopy was used and refined between 1974 and 1983 as a prenatal test to determine fetal status as well as obtain fetal blood and perform transfusions in some cases.

Blood transfusion

transfusionblood transfusionstransfusions
Valenti hypothesized in 1972 that the procedure he used to obtain fetal tissue could be used to obtain fetal blood, and in 1973, he was able to sample fetal vessels; fetoscopy was used and refined between 1974 and 1983 as a prenatal test to determine fetal status as well as obtain fetal blood and perform transfusions in some cases.

Miscarriage

miscarriedspontaneous abortionmiscarriages
PUBS has presented a more successful and less dangerous alternative to fetoscopy, which had a miscarriage risk of 5-10%.

Fluorescence in situ hybridization

FISHfluorescent in situ hybridizationfluorescence ''in situ'' hybridization
PUBS has been predominantly replaced by Fluorescence in situ hybridization (FISH) which is a more detailed investigation of chromosomal abnormalities.

Fetal viability

viabilityviableviability of the fetus
If the fetus is viable, the procedure is performed close to an operating room in case an emergency cesarean section is necessary due to complications caused by the procedure.