Pfizer

Pfizer Inc.Pfizer, Inc.Pfizer IncWarner-LambertPfizer PharmaceuticalsAgouron PharmaceuticalsPfizer, IncAlbert BourlaCharles Pfizer and CompanyChas. Pfizer & Co., Inc.
Pfizer Inc. (nyse: PFE, ) is an American multinational pharmaceutical corporation headquartered in New York City was founded in 1849, based in New York City and was listed on New York Stock Exchange.wikipedia
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GlaxoSmithKline

GlaxoSmithKline BeechamGSK
On December 19, 2018, Pfizer announced a joint merger of their consumer healthcare division with UK pharma giant GlaxoSmithKline; the British company will maintain a controlling share (listed at 68%).
Established in 2000 by a merger of Glaxo Wellcome and SmithKline Beecham, GSK was the world's seventh largest pharmaceutical company as of 2015, after Johnson & Johnson, Pfizer, Novartis, Merck, Hoffmann-La Roche and Sanofi.

Allergan

Allergan plcAllergan, PlcNaurex
In 2016, Pfizer Inc. was expected to merge with Allergan, Plc to create the Ireland-based "Pfizer plc" in a deal that would have been worth $160 billion.
In 2016, the U.S. Treasury blocked Actavis from executing what would have been the largest corporate tax inversion in history, in a $160 billion merger with Pfizer.

Charles Pfizer

Karl Pfizer
Pfizer was founded in New York City in 1849 by German-American Charles Pfizer and his cousin Charles F. Erhart from Ludwigsburg, Germany.
Karl Gustav Pfizer (March 22, 1824 – October 19, 1906), known as Charles Pfizer, was an American chemist who founded the Pfizer pharmaceutical company with his cousin Charles F. Erhart in 1849 as Charles Pfizer & Co.

Wyeth

American Home ProductsWyeth PharmaceuticalsA.H. Robins
In this decade, Pfizer grew by mergers, including those with Warner–Lambert (2000), Pharmacia (2003), and Wyeth (2009).
Its headquarters moved to Collegeville, Pennsylvania, and Madison, New Jersey, before its headquarters were consolidated with Pfizer's in New York City after the 2009 merger.

Williamsburg, Brooklyn

WilliamsburgWilliamsburg, New YorkWilliamsburgh
They launched the chemicals business Charles Pfizer and Company from a building at the intersection of Harrison Avenue and Bartlett Street in Williamsburg, Brooklyn, where they produced an antiparasitic called santonin.
German immigrant, chemist Charles Pfizer founded Pfizer Pharmaceutical in Williamsburg, and the company maintained an industrial plant in the neighborhood through 2007, although its headquarters were moved to Manhattan in the 1960s.

Torcetrapib

Development of torcetrapib, a drug that increases production of HDL, or "good cholesterol", which reduces LDL thought to be correlated to heart disease, was cancelled in December 2006.
Torcetrapib (CP-529,414, Pfizer) was a drug being developed to treat hypercholesterolemia (elevated cholesterol levels) and prevent cardiovascular disease.

Dow Jones Industrial Average

Dow JonesDJIADow
It is listed on the New York Stock Exchange, and its shares have been a component of the Dow Jones Industrial Average since 2004.

Visine

On June 26, 2006, Pfizer announced it would sell its Consumer Healthcare unit (manufacturer of Listerine, Nicorette, Visine, Sudafed and Neosporin) to Johnson & Johnson for $16.6 billion.
Johnson & Johnson acquired Visine, along with Pfizer's entire consumer healthcare portfolio, in December 2006.

Groton, Connecticut

GrotonGroton, Conn.Groton, CT
In the ensuing years, Pfizer carried out a massive restructuring that resulted in numerous site closures and the loss of jobs including Terre Haute, Indiana; Holland, Michigan; Groton, Connecticut; Brooklyn, New York; Sandwich, UK; and Puerto Rico.
The Naval Submarine Base New London is located in Groton, and the pharmaceutical company Pfizer is also a major employer.

Terre Haute, Indiana

Terre HauteTerre Haute, INTerra Haute, Indiana
In the ensuing years, Pfizer carried out a massive restructuring that resulted in numerous site closures and the loss of jobs including Terre Haute, Indiana; Holland, Michigan; Groton, Connecticut; Brooklyn, New York; Sandwich, UK; and Puerto Rico. The company also established an animal health division in 1959 with an 700 acre farm and research facility in Terre Haute, Indiana.
Following the war, Terre Haute gained several new factories: Pfizer Chemical (1948), Allis-Chalmers (1951), Columbia Records (1954), and Anaconda Aluminum (1959).

Piroxicam

FeldeneFeldene (piroxicam)Pirohexal-D
In 1980, they launched Feldene (piroxicam), a prescription anti-inflammatory medication that became Pfizer's first product to reach one billion dollars in total sales.
It was patented in 1968 by Pfizer and approved for medical use in 1979.

Sunitinib

Sutentsunitinib malateSU011248
These included sunitinib (Sutent), which was approved for human use by the FDA in January 2006, passed $1 billion in annual revenues for Pfizer in 2010.
Sunitinib (marketed as Sutent by Pfizer, and previously known as SU11248) is an oral, small-molecule, multi-targeted receptor tyrosine kinase (RTK) inhibitor that was approved by the FDA for the treatment of renal cell carcinoma (RCC) and imatinib-resistant gastrointestinal stromal tumor (GIST) on January 26, 2006.

Listerine

Listerine mouthwashListerine PocketPakListermint
On June 26, 2006, Pfizer announced it would sell its Consumer Healthcare unit (manufacturer of Listerine, Nicorette, Visine, Sudafed and Neosporin) to Johnson & Johnson for $16.6 billion.
Originally marketed by the Lambert Pharmacal Company (which later became Warner-Lambert), Listerine has been manufactured and distributed by Johnson & Johnson since that company's acquisition of Pfizer's consumer healthcare division in late December 2006.

King Pharmaceuticals

AlpharmaKing Pharmaceuticals, Inc.Monarch Pharmaceuticals
In October 2010, Pfizer agreed to buy King Pharmaceuticals for $3.6 billion in cash or $14.25 per share: an approximately 40% premium over King's closing share price October 11, 2010.
King Pharmaceuticals, is a wholly owned subsidiary of Pfizer based in Bristol, Tennessee.

New York City

New YorkNew York, New YorkNew York City, New York
Pfizer was founded in New York City in 1849 by German-American Charles Pfizer and his cousin Charles F. Erhart from Ludwigsburg, Germany. Pfizer Inc. (nyse: PFE, ) is an American multinational pharmaceutical corporation headquartered in New York City was founded in 1849, based in New York City and was listed on New York Stock Exchange.
By mid-2014, Accelerator, a biotech investment firm, had raised more than US$30 million from investors, including Eli Lilly and Company, Pfizer, and Johnson & Johnson, for initial funding to create biotechnology startups at the Alexandria Center for Life Science, which encompasses more than 700000 sqft on East 29th Street and promotes collaboration among scientists and entrepreneurs at the center and with nearby academic, medical, and research institutions.

Oxytetracycline

TerramycinOxytetracycline hydrochlorideE703
They discovered Terramycin (oxytetracycline) in 1950, and this changed the company from a manufacturer of fine chemicals to a research-based pharmaceutical company.
It was first found near Pfizer laboratories in a soil sample yielding the soil actinomycete, Streptomyces rimosus by Finlay et al. In 1950, a celebrated American chemist, Robert B Woodward, worked out the chemical structure of oxytetracycline, enabling Pfizer to mass-produce the drug under the trade name, Terramycin.

Pharmacia & Upjohn

In 1995, Upjohn merged with Pharmacia, to form Pharmacia & Upjohn.
Today the remainder of the company is owned by Pfizer.

Esperion Therapeutics

In 2003, the company acquired Esperion Therapeutics for $1.3 billion (later selling the unit in 2008), protecting Lipitor from ETC-216.
Pfizer acquired the original Esperion in 2004 for US$1.3 billion as a defensive move to prevent ETC-216 from falling into competitors' hands.

Charles F. Erhart

Pfizer was founded in New York City in 1849 by German-American Charles Pfizer and his cousin Charles F. Erhart from Ludwigsburg, Germany.
Charles F. Erhart (born 1821 in Ludwigsburg as Karl Erhart – 1891) was a German-born American chemist who co-founded Charles Pfizer & Company together with Charles Pfizer, his cousin and future brother-in-law.

Array BioPharma

In June, Pfizer announced it would acquire Array Biopharma for $10.6 billion boosting its oncology pipeline.
The company is a subsidiary of Pfizer.

Kalamazoo, Michigan

KalamazooKalamazoo, MIKalamazoo Michigan
The Upjohn Company was a pharmaceutical manufacturing firm founded in 1886 in Kalamazoo, Michigan, by Dr. William E. Upjohn, an 1875 graduate of the University of Michigan medical school.
The Upjohn Company was a pharmaceutical research and manufacturing firm founded in 1886 in Kalamazoo; through a series of mergers and acquisitions that took place between 1995 and 2003, the Upjohn Company assets became a part of the Pfizer Corporation.

COX-2 inhibitor

COX-2 selective inhibitorCOX-2 inhibitorsCOX inhibitor
The merger was again driven in part by the desire to acquire full rights to a product, this time Celebrex (celecoxib), the COX-2 selective inhibitor previously jointly marketed by Searle (acquired by Pharmacia) and Pfizer.
Brigham Young University has sued Pfizer, alleging breach of contract from relations BYU had with the company at the time of Dr. Simmons's work.

Tax inversion

corporate inversioncorporate tax inversioncorporate tax inversions
On April 6, 2016, Pfizer and Allergan announced they would be calling off the merger after the Obama administration introduced new laws intended to limit corporate tax inversions (the extent to which companies could move their headquarters overseas in order to reduce the amount of taxes they pay).
New US Treasury rules in 2014–16 blocked several major inversions (e.g. 2016 USD$160 billion Pfizer–Allergan plc inversion, and the 2015 USD$54 billion AbbVie–Shire plc inversion), and the Tax Cuts and Jobs Act of 2017 (TCJA) further reduced the taxation incentives of inversions.

University of Michigan

MichiganUniversity of Michigan, Ann ArborUniversity of Michigan at Ann Arbor
The Upjohn Company was a pharmaceutical manufacturing firm founded in 1886 in Kalamazoo, Michigan, by Dr. William E. Upjohn, an 1875 graduate of the University of Michigan medical school.
In 2009, the university consummated a deal to purchase a facility formerly owned by Pfizer.

AstraZeneca

Astra ZenecaAstraZeneca PharmaceuticalsAstra
Two days later, Pfizer announced it would acquire AstraZenecas small-molecule antibiotics business for $1.575 billion merging it into its Essential Medicines business In the same month the company licensed the anti-CTLA4 monoclonal antibody, ONC-392, from OncoImmune.
On 19 May 2014 AstraZeneca rejected a "final offer" from Pfizer of £ 55 per share, which valued the company at £69.4 billion (US$ 117 billion).