A report on Plasmodium falciparum and Plasmodium vivax
Although it is less virulent than Plasmodium falciparum, the deadliest of the five human malaria parasites, P. vivax malaria infections can lead to severe disease and death, often due to splenomegaly (a pathologically enlarged spleen).
- Plasmodium vivaxIn 1900, the Italian zoologist Giovanni Battista Grassi categorized Plasmodium species based on the timing of fever in the patient; malignant tertian malaria was caused by Laverania malariae (now P. falciparum), benign tertian malaria by Haemamoeba vivax (now P. vivax), and quartan malaria by Haemamoeba malariae (now P. malariae).
- Plasmodium falciparum7 related topics with Alpha
Malaria
6 linksMosquito-borne infectious disease that affects humans and other animals.
Mosquito-borne infectious disease that affects humans and other animals.
Most deaths are caused by P. falciparum, whereas P. vivax, P. ovale, and P. malariae generally cause a milder form of malaria.
Plasmodium
4 linksGenus of unicellular eukaryotes that are obligate parasites of vertebrates and insects.
Genus of unicellular eukaryotes that are obligate parasites of vertebrates and insects.
Over the course of the 20th century, many other species were discovered in various hosts and classified, including five species that regularly infect humans: P. vivax, P. falciparum, P. malariae, P. ovale, and P. knowlesi.
Chloroquine
3 linksMedication primarily used to prevent and treat malaria in areas where malaria remains sensitive to its effects.
Medication primarily used to prevent and treat malaria in areas where malaria remains sensitive to its effects.
]]Chloroquine has been used in the treatment and prevention of malaria from Plasmodium vivax, ''[[Plasmodium ovale|P.
It is generally not used for Plasmodium falciparum as there is widespread resistance to it.
Antimalarial medication
3 linksAntimalarial medications or simply antimalarials are a type of antiparasitic chemical agent, often naturally derived, that can be used to treat or to prevent malaria, in the latter case, most often aiming at two susceptible target groups, young children and pregnant women.
Antimalarial medications or simply antimalarials are a type of antiparasitic chemical agent, often naturally derived, that can be used to treat or to prevent malaria, in the latter case, most often aiming at two susceptible target groups, young children and pregnant women.
Practice in treating cases of malaria is most often based on the concept of combination therapy (e.g., using agents such as artemether and lumefantrine against chloroquine-resistant Plasmodium falciparum infection), since this offers advantages including reduced risk of treatment failure, reduced risk of developed resistance, as well as the possibility of reduced side-effects.
Quinine is an alkaloid that acts as a blood schizonticidal and weak gametocide against Plasmodium vivax and Plasmodium malariae.
Plasmodium malariae
2 linksParasitic protozoan that causes malaria in humans.
Parasitic protozoan that causes malaria in humans.
It is one of several species of Plasmodium parasites that infect other organisms as pathogens, also including Plasmodium falciparum and Plasmodium vivax, responsible for most malarial infection.
Duffy antigen system
1 linksProtein that in humans is encoded by the ACKR1 gene.
Protein that in humans is encoded by the ACKR1 gene.
The protein is also the receptor for the human malarial parasites Plasmodium vivax, Plasmodium knowlesi and simian malarial parasite Plasmodium cynomolgi.
The Andaman and Nicobar Islands, now part of India, were originally inhabited by 14 aboriginal tribes. Several of these have gone extinct. One surviving tribe—the Jarawas—live in three jungle areas of South Andaman and one jungle area in Middle Andaman. The area is endemic for malaria. The causative species is Plasmodium falciparum: there is no evidence for the presence of Plasmodium vivax. Blood grouping revealed an absence of both Fy(a) and Fy(b) antigens in two areas and a low prevalence in two others.
Glucose-6-phosphate dehydrogenase deficiency
1 linksMost common enzyme deficiency worldwide, is an inborn error of metabolism that predisposes to red blood cell breakdown.
Most common enzyme deficiency worldwide, is an inborn error of metabolism that predisposes to red blood cell breakdown.
Both variants are believed to stem from a strongly protective effect against Plasmodium falciparum and Plasmodium vivax malaria.