Psychomotor agitation

agitationrestlessnessexcitementagitatedexcitationPsychomotorsevere agitationincrease in energy of psychomotor activityincreased movementoverexcitability
Psychomotor agitation is a spectrum of disorders characterized by unintentional and purposeless motions and restlessness, often accompanied by emotional distress, but not always.wikipedia
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Major depressive disorder

depressionclinical depressionmajor depression
Psychomotor agitation is typically found in major depressive disorder or obsessive-compulsive disorder, and sometimes the manic phase in bipolar disorder, though it can also be a result of an excess intake of stimulants.
Family and friends may notice that the person's behavior is either agitated or lethargic.

Bipolar disorder

bipolarmanic depressionmanic depressive
Psychomotor agitation is typically found in major depressive disorder or obsessive-compulsive disorder, and sometimes the manic phase in bipolar disorder, though it can also be a result of an excess intake of stimulants.
The core symptom of mania involves an increase in energy of psychomotor activity.

Excited delirium

Bell's maniadeliriumprolonged, violent resistance
Excited delirium, also known as agitated delirium, is a condition that presents with psychomotor agitation, delirium, and sweating.

Posttraumatic stress disorder

post-traumatic stress disorderPTSDpost traumatic stress disorder
Dopamine levels in a person with PTSD can contribute to symptoms: low levels can contribute to anhedonia, apathy, impaired attention, and motor deficits; high levels can contribute to psychosis, agitation, and restlessness.

Alcohol withdrawal syndrome

alcohol withdrawalwithdrawalalcohol
To be classified as alcohol withdrawal syndrome, patients must exhibit at least two of the following symptoms: increased hand tremor, insomnia, nausea or vomiting, transient hallucinations (auditory, visual or tactile), psychomotor agitation, anxiety, tonic-clonic seizures, and autonomic instability.

Cocaine

cokecocaine traffickingcrack
Mental effects may include loss of contact with reality, an intense feeling of happiness, or agitation.

Midazolam

VersedDormicumMidazolam hydrochloride
Intramuscular midazolam, lorazepam, or another benzodiazepine can be used to both sedate agitated patients, and control semi-involuntary muscle movements in cases of suspected akathisia.
Midazolam, marketed under the trade name Versed, among others, is a benzodiazepine medication used for anesthesia, procedural sedation, trouble sleeping, and severe agitation.

Lorazepam

Ativanbenzodiazepine lorazepamdrug of the same name
Intramuscular midazolam, lorazepam, or another benzodiazepine can be used to both sedate agitated patients, and control semi-involuntary muscle movements in cases of suspected akathisia.
While it can be used for severe agitation, midazolam is usually preferred.

Akathisia

akathisia, drug-inducedagitationakathesia
Intramuscular midazolam, lorazepam, or another benzodiazepine can be used to both sedate agitated patients, and control semi-involuntary muscle movements in cases of suspected akathisia.
Akathisia is a movement disorder characterized by a feeling of inner restlessness and inability to stay still.

Methylphenidate

RitalinConcertaMethylin
The symptoms of a moderate acute overdose on methylphenidate primarily arise from central nervous system overstimulation; these symptoms include: vomiting, agitation, tremors, hyperreflexia, muscle twitching, euphoria, confusion, hallucinations, delirium, hyperthermia, sweating, flushing, headache, tachycardia, heart palpitations, cardiac arrhythmias, hypertension, mydriasis, and dryness of mucous membranes.

Ziprasidone

Geodon
Recently, three atypical antipsychotics, olanzapine, aripiprazole and ziprasidone, have become available and FDA approved as an instant release intramuscular injection formulations to control acute agitation.
The IM form may be used for acute agitation in people with schizophrenia.

Benzodiazepine

benzodiazepinesbenzodiazapinesbenzo
Intramuscular midazolam, lorazepam, or another benzodiazepine can be used to both sedate agitated patients, and control semi-involuntary muscle movements in cases of suspected akathisia.
These properties make benzodiazepines useful in treating anxiety, insomnia, agitation, seizures, muscle spasms, alcohol withdrawal and as a premedication for medical or dental procedures.

Olanzapine

ZyprexaZyprexa (olanzapine)adverse effects
Recently, three atypical antipsychotics, olanzapine, aripiprazole and ziprasidone, have become available and FDA approved as an instant release intramuscular injection formulations to control acute agitation.
Symptoms of an overdose include tachycardia, agitation, dysarthria, decreased consciousness, and coma.

Excoriation disorder

dermatillomaniaskin pickingskin-picking
In more severe cases, the motions may become harmful to the individual, such as ripping, tearing, or chewing at the skin around one's fingernails, lips, or other body parts to the point of bleeding.

Stimulant

stimulantspsychostimulantpsychostimulants
Psychomotor agitation is typically found in major depressive disorder or obsessive-compulsive disorder, and sometimes the manic phase in bipolar disorder, though it can also be a result of an excess intake of stimulants.

Hyponatremia

Hyponatraemialow blood sodiumlow blood sodium levels
It can also be caused by severe hyponatremia.

Antipsychotic

antipsychoticsneurolepticneuroleptics
In other cases, psychomotor agitation can be caused by antipsychotic medications.

Schizophrenia

schizophrenicschizophrenicspositive symptoms

Obsessive–compulsive disorder

obsessive-compulsive disorderobsessive compulsive disorderOCD
Psychomotor agitation is typically found in major depressive disorder or obsessive-compulsive disorder, and sometimes the manic phase in bipolar disorder, though it can also be a result of an excess intake of stimulants.