A report on Purdue Pharma

American privately held pharmaceutical company founded by John Purdue Gray.

- Purdue Pharma

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Sackler family

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The Sackler family is an American family who founded and own the pharmaceutical companies Purdue Pharma and Mundipharma.

The Sackler Crossing at the Royal Botanic Gardens, Kew

Mortimer Sackler

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The Sackler Crossing at the Royal Botanic Gardens, Kew

Mortimer David Sackler (December 7, 1916 – March 24, 2010) was an American-born British psychiatrist and entrepreneur who was a co-owner, with his brother Raymond, of Purdue Pharma.

Raymond Sackler

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American physician and businessman.

American physician and businessman.

He acquired Purdue Pharma together with his brothers Arthur M. Sackler and Mortimer Sackler.

Oxycodone

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Semi-synthetic opioid medication used for treatment of moderate to severe pain.

Semi-synthetic opioid medication used for treatment of moderate to severe pain.

A liquid solution containing 10mg of oxycodone per 1ml
Main side effects of oxycodone
Two tablets (10 mg) of oxycodone and safety blisters
Canadian oxycodone HCL/acetaminophen 5/325 mg tablet

A July 1996 study independent of Purdue Pharma, the drug's originator, found the controlled-release formulation had a variable duration of action ranging from 10 to 12 hours.

Purdue Pharmaceuticals, which heavily promoted oxycodone, increasing their earning to US$35billion by 2017.

Opioid epidemic in the United States

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Extensive ongoing overuse of opioid medications, both from medical prescriptions and from illegal sources.

Extensive ongoing overuse of opioid medications, both from medical prescriptions and from illegal sources.

Purdue Pharmaceuticals, which heavily promoted oxycodone, increasing their earning to US$35billion by 2017.
A chart outlining the structural features that define opiates and opioids, including distinctions between semi-synthetic and fully synthetic opiate structures
Annual fentanyl seizures in Mexico.
Of the 64,070 overdose deaths in the US in 2016, opioids were involved in 42,249. In 2016, the five states with the highest rates of death due to drug overdose were West Virginia (52.0 per 100,000), Ohio (39.1 per 100,000), New Hampshire (39.0 per 100,000), Pennsylvania (37.9 per 100,000) and Kentucky (33.5 per 100,000).
Drug overdose deaths in the US per 100,000 people by state.
Public bathroom illuminated with blue lights to deter the use of drugs, supposedly making it harder to find veins
Opiate self-injection paraphernalia
The top line represents the yearly number of benzodiazepine deaths that involved opioids in the United States. The bottom line represents benzodiazepine deaths that did not involve opioids.<ref name=NIDA-deaths/>
Opioid involvement in cocaine overdose deaths. Green line is cocaine and any opioid. Gray line is cocaine without any opioids. Yellow line is cocaine and other .<ref name=NIDA-deaths/>
2 mg of Fentanyl. This is a lethal dose to most people.<ref>Fentanyl. Image 4 of 17. U.S. DEA (Drug Enforcement Administration).</ref> Diameter of a US penny is 19.05 mm, or 0.75 inches.
U.S. yearly deaths involving other, predominately Fentanyl.<ref name=NIDA-deaths/>

Purdue Pharma hosted over forty promotional conferences at three select locations in the southwest and southeast of the United States.

Arthur M. Sackler

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American psychiatrist and marketer of pharmaceuticals whose fortune originated in medical advertising and trade publications.

American psychiatrist and marketer of pharmaceuticals whose fortune originated in medical advertising and trade publications.

Since his death, Sackler's reputation has been tarnished due to his company Purdue Pharma's role in the opioid crisis.

P.A.I.N.

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P.A.I.N. (Prescription Addiction Intervention Now) is an advocacy organization founded by Nan Goldin to respond to the opioid crisis, specifically targeting the Sackler Family for manufacturing and distributing the drug Oxycontin through their corporation Purdue Pharma LP.

Goldin in 2017

Nan Goldin

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American photographer and activist.

American photographer and activist.

Goldin in 2017
The Hug, NYC, 1980, Cibachrome print by Goldin.
Christmas at the Other Side, Boston, 1972, by Goldin.

This led to her setting up a campaign called Prescription Addiction Intervention Now (P.A.I.N.) pursuing social media activism directed against the Sackler family for their involvement in Purdue Pharma, manufacturers of OxyContin.

Hydrocodone and paracetamol (acetaminophen) 10-325 tablets (Mallinckrodt)

Hydrocodone

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Opioid used to treat pain and as a cough suppressant.

Opioid used to treat pain and as a cough suppressant.

Hydrocodone and paracetamol (acetaminophen) 10-325 tablets (Mallinckrodt)

Controlled-release hydrocodone (Hysingla ER by Purdue Pharma, Zohydro ER)

A 10mg MS Continus-branded extended-release morphine tablet displaying the Napp logo. This tablet was manufactured by Bard Pharmaceuticals Ltd, a subsidiary of Napp pharmaceuticals, and distributed by Mundipharma.

Napp Pharmaceuticals

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Private pharmaceutical company in Cambridge, United Kingdom that was founded in 1923 and bought by the Sackler family in 1966.

Private pharmaceutical company in Cambridge, United Kingdom that was founded in 1923 and bought by the Sackler family in 1966.

A 10mg MS Continus-branded extended-release morphine tablet displaying the Napp logo. This tablet was manufactured by Bard Pharmaceuticals Ltd, a subsidiary of Napp pharmaceuticals, and distributed by Mundipharma.
The headquarters of Napp Pharmaceuticals, located in the Cambridge Science Park.

Headquartered together with the related Napp Research Centre in the Cambridge Science Park since the 1980's, it is a sister company of Purdue Pharma and Mundipharma, all of which are owned by the descendants of Mortimer and Raymond Sackler.