Reactive arthritis

arthritis, reactiveReactive arthropathyreiter diseaseReiter's diseasejoint inflammationR'''eactive arthritisReiter syndrome
Reactive arthritis, formerly known as Reiter's syndrome, is a form of inflammatory arthritis that develops in response to an infection in another part of the body (cross-reactivity).wikipedia
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Arthritis

arthriticjoint inflammationarthritic changes
Reactive arthritis, formerly known as Reiter's syndrome, is a form of inflammatory arthritis that develops in response to an infection in another part of the body (cross-reactivity). Repeated attacks over many years are common, and patients sometimes end up with chronic and disabling arthritis, heart disease, amyloid deposits, ankylosing spondylitis, immunoglobulin A nephropathy, cardiac conduction abnormalities, or aortitis with aortic regurgitation.

Urethritis

inflammation in the urethrainflammation of the penile urethrainflammation of the urethra
The manifestations of reactive arthritis include the following triad of symptoms: an inflammatory arthritis of large joints, inflammation of the eyes in the form of conjunctivitis or uveitis, and urethritis in men or cervicitis in women.
Urethritis is part of triad of reactive arthritis.

HLA-B27

HLA B27B27HLA-B*27
Reactive arthritis is an RF-seronegative, HLA-B27-linked arthritis often precipitated by genitourinary or gastrointestinal infections.
Diseases associated with the HLA-B27 subtype can be remembered with the mnemonic PAIR, and include Psoriasis, Ankylosing spondylitis, Inflammatory bowel disease, and Reactive arthritis.

Balanitis circinata

circinate balanitisring shaped lesions on their penis
Patients can also present with mucocutaneous lesions, as well as psoriasis-like skin lesions such as circinate balanitis, and keratoderma blennorrhagicum.
Balanitis circinata (also known as circinate balanitis) is a skin condition of reactive arthritis comprising a serpiginous ring-shaped dermatitis of the glans penis.

Plantar fasciitis

plantar fascia injuryDancer's heelHeel spur syndrome
Other conditions with similar symptoms include osteoarthritis, ankylosing spondylitis, heel pad syndrome, and reactive arthritis.

Conjunctivitis

pink eyepinkeyeblepharoconjunctivitis
The manifestations of reactive arthritis include the following triad of symptoms: an inflammatory arthritis of large joints, inflammation of the eyes in the form of conjunctivitis or uveitis, and urethritis in men or cervicitis in women.
Conjunctivitis is part of the triad of reactive arthritis, which is thought to be caused by autoimmune cross-reactivity following certain bacterial infections.

Keratoderma blennorrhagicum

Keratoderma blennorrhagicaKeratoderma blenorrhagicum
Patients can also present with mucocutaneous lesions, as well as psoriasis-like skin lesions such as circinate balanitis, and keratoderma blennorrhagicum.
Keratoderma blennorrhagicum is commonly seen as an additional feature of reactive arthritis in almost 15% of male patients.

Enthesitis

Enthesitis-related arthritis
Enthesitis can involve the Achilles tendon resulting in heel pain.
It is associated with HLA B27 arthropathies such as ankylosing spondylitis, psoriatic arthritis, and reactive arthritis.

Aortic insufficiency

aortic regurgitationaortic valve insufficiencyAortic valve regurgitation
Repeated attacks over many years are common, and patients sometimes end up with chronic and disabling arthritis, heart disease, amyloid deposits, ankylosing spondylitis, immunoglobulin A nephropathy, cardiac conduction abnormalities, or aortitis with aortic regurgitation.
In terms of the cause of aortic insufficiency, is often due to the aortic root dilation (annuloaortic ectasia), which is idiopathic in over 80% of cases, but otherwise may result from aging, syphilitic aortitis, osteogenesis imperfecta, aortic dissection, Behçet's disease, reactive arthritis and systemic hypertension.

Hans Reiter (physician)

Hans Conrad Julius ReiterHans Reiter
The term "reactive arthritis" is preferred and increasingly used as a substitute for this designation because Hans Conrad Julius Reiter was not the first to describe the syndrome, his conclusions regarding its pathogenesis were incorrect, and because he committed war crimes as a Nazi at Buchenwald concentration camp during World War II.
In 1977, a group of doctors began a campaign to replace the term "Reiter's syndrome" with "reactive arthritis".

Ankylosing spondylitis

Bekhterev’s DiseaseBekhterev's Diseasespondylitis, ankylosing
Repeated attacks over many years are common, and patients sometimes end up with chronic and disabling arthritis, heart disease, amyloid deposits, ankylosing spondylitis, immunoglobulin A nephropathy, cardiac conduction abnormalities, or aortitis with aortic regurgitation.
This interaction is not proven to involve a self-antigen, and at least in the related reactive arthritis, which follows infections, the antigens involved are likely to be derived from intracellular microorganisms.

Aphthous stomatitis

aphthous ulceraphthous ulcerscanker sores
Other examples of systemic conditions associated with aphthous-like ulceration include reactive arthritis, and recurrent erythema multiforme.

Geographic tongue

migratory stomatitis
Lesions that are histologically indistinguishable from geographic tongue may also be diagnosed in reactive arthritis (arthritis, uveitis/conjunctivitis and urethritis).

Spondyloarthropathy

spondyloarthropathiesspondyloarthritisspondylarthritis
Reactive arthritis is an RF-seronegative, HLA-B27-linked arthritis often precipitated by genitourinary or gastrointestinal infections.

Nonsteroidal anti-inflammatory drug

NSAIDNSAIDsnon-steroidal anti-inflammatory drug
Analgesics, particularly NSAIDs, are used.

Shigella

Shigella species.Shigella typhi
The most common triggers are intestinal infections (with Salmonella, Shigella or Campylobacter) and sexually transmitted infections (with Chlamydia trachomatis), however, it also can happen after group A streptococcal infections. Other bacteria known to cause reactive arthritis which are more common worldwide are Ureaplasma urealyticum, Salmonella spp., Shigella spp., Yersinia spp., and Campylobacter spp.
Shigella is implicated as one of the pathogenic causes of reactive arthritis worldwide.

Dysuria

painful urinationburning with urinationpain with urination

Gout

gouty arthritispodagragout attack
Other conditions that can look similar include pseudogout, rheumatoid arthritis, psoriatic arthritis, and reactive arthritis.

Dactylitis

sausage digitsswelling in the hands and feetswelling of entire fingers and toes
In reactive arthritis, sausage fingers occur due to synovitis.

Yersinia

Yersinia infectionyersinia infections
Other bacteria known to cause reactive arthritis which are more common worldwide are Ureaplasma urealyticum, Salmonella spp., Shigella spp., Yersinia spp., and Campylobacter spp.
Yersinia is implicated as one of the causes of reactive arthritis worldwide.

Uveitis

iritisiridocyclitisanterior uveitis
The manifestations of reactive arthritis include the following triad of symptoms: an inflammatory arthritis of large joints, inflammation of the eyes in the form of conjunctivitis or uveitis, and urethritis in men or cervicitis in women.

Sulfasalazine

sulphasalazineAzulfidineSalazopyrine
Steroids, sulfasalazine and immunosuppressants may be needed for patients with severe reactive symptoms that do not respond to any other treatment.
It is also indicated for use in rheumatoid arthritis and used in other types of inflammatory arthritis (e.g. psoriatic arthritis and reactive arthritis).

Pat Buchanan

Patrick J. BuchananBuchananBuchanan, Pat
The District of Columbia draft board exempted Buchanan from military service because of reactive arthritis, classifying him as 4-F.

Ian Murray (footballer)

Ian Murray
It was eventually diagnosed that Murray was suffering from reactive arthritis.

Mark St. John

St. John developed reactive arthritis, which caused his hands and arms to swell.