Red pulp

Red Pulp Macrophagesplenic pulpSplenic red pulp
The red pulp of the spleen is composed of connective tissue known also as the cords of Billroth and many splenic sinusoids that are engorged with blood, giving it a red color.wikipedia
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Spleen

splenicsplenetichilum
The red pulp of the spleen is composed of connective tissue known also as the cords of Billroth and many splenic sinusoids that are engorged with blood, giving it a red color.
A study published in 2009 using mice found that the red pulp of the spleen forms a reservoir that contains over half of the body's monocytes.

Cords of Billroth

Billroth's cordssplenic cords
The red pulp of the spleen is composed of connective tissue known also as the cords of Billroth and many splenic sinusoids that are engorged with blood, giving it a red color.
The Cords of Billroth (also known as splenic cords or red pulp cords) are found in the red pulp of the spleen between the sinusoids, consisting of fibrils and connective tissue cells with a large population of monocytes and macrophages.

Marginal zone

zone
The spleen is made of red pulp and white pulp, separated by the marginal zone; 76-79% of a normal spleen is red pulp.
The marginal zone is the region at the interface between the non-lymphoid red pulp and the lymphoid white-pulp of the spleen.

Monocyte

monocytesmonocyticmononuclear
The red pulp also acts as a large reservoir for monocytes.
About half of the body's monocytes are stored as a reserve in the spleen in clusters in the red pulp's Cords of Billroth.

Macrophage

macrophagesM2 macrophagesTissue macrophages
Worn-out or abnormal red cells attempting to squeeze through the narrow intercellular spaces become badly damaged, and are subsequently devoured by macrophages in the red pulp.

White pulp

splenic lymphoid nodulesMalpighian bodies of the spleenMalpighian corpuscle
The spleen is made of red pulp and white pulp, separated by the marginal zone; 76-79% of a normal spleen is red pulp.

Trabeculae of spleen

splenic trabeculaetrabecula
The spleen therefore consists of a number of small spaces or areolae, formed by the trabeculae; in these areolae is contained the splenic pulp.

Capillary

capillariessinusoidscapillary bed
The red pulp of the spleen is composed of connective tissue known also as the cords of Billroth and many splenic sinusoids that are engorged with blood, giving it a red color.

Antigen

antigensantigenicantigenic proteins
Its primary function is to filter the blood of antigens, microorganisms, and defective or worn-out red blood cells.

Lymphocyte

lymphocyteslymphocyticlymphoid cells
Unlike white pulp, which mainly contains lymphocytes such as T cells, red pulp is made up of several different types of blood cells, including platelets, granulocytes, red blood cells, and plasma.

T cell

T cellsT-cellT-cells
Unlike white pulp, which mainly contains lymphocytes such as T cells, red pulp is made up of several different types of blood cells, including platelets, granulocytes, red blood cells, and plasma.

Platelet

plateletsplatelet aggregationplatelet count
Unlike white pulp, which mainly contains lymphocytes such as T cells, red pulp is made up of several different types of blood cells, including platelets, granulocytes, red blood cells, and plasma.

Granulocyte

granulocytesgranulocytopeniapolymorphonuclear leukocyte
Unlike white pulp, which mainly contains lymphocytes such as T cells, red pulp is made up of several different types of blood cells, including platelets, granulocytes, red blood cells, and plasma.

Red blood cell

red blood cellserythrocyteserythroid
Unlike white pulp, which mainly contains lymphocytes such as T cells, red pulp is made up of several different types of blood cells, including platelets, granulocytes, red blood cells, and plasma.

Blood plasma

plasmaserumblood serum
Unlike white pulp, which mainly contains lymphocytes such as T cells, red pulp is made up of several different types of blood cells, including platelets, granulocytes, red blood cells, and plasma.

Trabecular veins

trabecular vein
The splenic sinusoids, are wide vessels that drain into pulp veins which themselves drain into trabecular veins.

Endothelium

endothelialendothelial cellsendothelial cell
Gaps in the endothelium lining the sinusoids mechanically filter blood cells as they enter the spleen.

Blood

human bloodhematologicaloxygen consumption

White blood cell

leukocyteleukocyteswhite blood cells

Lymphoid leukemia

lymphocytic leukemialymphatic leukemiaB cell leukemia
In lymphoid leukemia, the white pulp of the spleen hypertrophies and the red pulp shrinks.

Myeloid leukemia

myeloid leukaemiamyelogenous leukemialeukemia, myeloid
In myeloid leukemia, the white pulp atrophies and the red pulp expands.

High endothelial venules

high endothelial venuleHEVs (high endotelial venule)high endothelial cells
In humans, HEVs are found in all secondary lymphoid organs (with the exception of spleen, where blood exits through open arterioles and enters the red pulp), including hundreds of lymph nodes dispersed in the body, tonsils and adenoids in the pharynx, Peyer's patches (PIs) in the small intestine, appendix, and small aggregates of lymphoid tissue in the stomach and large intestine.