Rhinovirus

human rhinoviruscold virusRhinovirus ARhinovirus BRhinovirus CcoldHRV14rhinoviralrhinoviral diseaserhinoviral receptor binding
The rhinovirus (from the Greek ῥίς rhis "nose", ῥινός rhinos "of the nose", and the Latin vīrus) is the most common viral infectious agent in humans and is the predominant cause of the common cold.wikipedia
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Common cold

coldcoldsnasopharyngitis
The rhinovirus (from the Greek ῥίς rhis "nose", ῥινός rhinos "of the nose", and the Latin vīrus) is the most common viral infectious agent in humans and is the predominant cause of the common cold.
Well over 200 virus strains are implicated in causing the common cold, with rhinoviruses being the most common.

Rhinitis

coryzaseasonal allergic rhinitisrhinitis, allergic, perennial
Symptoms include sore throat, runny nose, nasal congestion, sneezing and cough; sometimes accompanied by muscle aches, fatigue, malaise, headache, muscle weakness, or loss of appetite.
Rhinitis is commonly caused by a viral or bacterial infection, including the common cold, which is caused by Rhinoviruses, Coronaviruses, and influenza viruses, others caused by adenoviruses, human parainfluenza viruses, human respiratory syncytial virus, enteroviruses other than rhinoviruses, metapneumovirus, and measles virus, or bacterial sinusitis, which is commonly caused by Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis.

ICAM-1

CD54ICAM1(ICAM-1
Rhinovirus A and B bind to ICAM-1 (Inter-Cellular Adhesion Molecule 1) also known as CD54 (Cluster of Differentiation 54) receptors on respiratory epithelial cells while rhinovirus C uses cadherin-related family member 3 (CDHR3) to mediate cellular entry.
It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by rhinovirus as a receptor for entry into respiratory epithelium.

Pharyngitis

throat infectionsore throatthroat infections
Symptoms include sore throat, runny nose, nasal congestion, sneezing and cough; sometimes accompanied by muscle aches, fatigue, malaise, headache, muscle weakness, or loss of appetite.

Cadherin related family member 3

CDHR3cadherin-related family member 3 (CDHR3)CDHR3 receptor
Rhinovirus A and B bind to ICAM-1 (Inter-Cellular Adhesion Molecule 1) also known as CD54 (Cluster of Differentiation 54) receptors on respiratory epithelial cells while rhinovirus C uses cadherin-related family member 3 (CDHR3) to mediate cellular entry.
Subsequent studies have suggested that CDHR3 is a receptor for a subtype of rhinovirus.

Influenza

fluhuman fluthe flu
By comparison, other viruses, such as smallpox and vaccinia, are around 10 times larger at about 300 nanometers; while flu viruses are around 80–120 nm.
In contrast to the rhinovirus that causes the common cold, influenza does cause tissue damage, so symptoms are not entirely due to the inflammatory response.

Picornavirus

Picornaviridaepicornavirusespicorna
Rhinoviruses belong to the genus Enterovirus in the family Picornaviridae. Pleconaril is an orally bioavailable antiviral drug being developed for the treatment of infections caused by picornaviruses.
Notable examples are Enterovirus (including Rhinovirus and Poliovirus), Aphthovirus, Cardiovirus, and Hepatovirus genera.

Enterovirus 71

71Enterovirus 71 epidemicEV71
This virus is a member of the enterovirus species A. Species A was formerly assigned to the genus Rhinovirus.

Pleconaril

Pleconaril is an orally bioavailable antiviral drug being developed for the treatment of infections caused by picornaviruses.
Pleconaril, administered either orally or intranasally, is active against viruses in the Picornaviridae family, including Enterovirus and Rhinovirus.

Poliovirus

polio viruspoliopolioviruses
The lead compound in this series, IMP-1088, very potently inhibited host myristoylation of viral capsid protein and prevented infectious virus formation, rescuing the viability of cells in culture which had been exposed to a variety of rhinovirus serotypes, or to related picornaviruses including poliovirus and foot-and-mouth-disease virus.
Poliovirus is structurally similar to other human enteroviruses (coxsackieviruses, echoviruses, and rhinoviruses), which also use immunoglobulin-like molecules to recognize and enter host cells.

Enterovirus E

It is also smoother than the related human rhinovirus due to the extension of a surface loop in BEV.

IMP-1088

The lead compound in this series, IMP-1088, very potently inhibited host myristoylation of viral capsid protein and prevented infectious virus formation, rescuing the viability of cells in culture which had been exposed to a variety of rhinovirus serotypes, or to related picornaviruses including poliovirus and foot-and-mouth-disease virus.
IMP-1088 is an enzyme inhibitor of the human N-myristoyltransferases NMT1 and NMT2 capable of preventing rhinoviral replication, an area of research relating to potential treatment of the common cold.

Ancient Greek

GreekClassical GreekGr.
The rhinovirus (from the Greek ῥίς rhis "nose", ῥινός rhinos "of the nose", and the Latin vīrus) is the most common viral infectious agent in humans and is the predominant cause of the common cold.

Latin

Latin languageLat.la
The rhinovirus (from the Greek ῥίς rhis "nose", ῥινός rhinos "of the nose", and the Latin vīrus) is the most common viral infectious agent in humans and is the predominant cause of the common cold.

Virus

virusesviralvirion
The rhinovirus (from the Greek ῥίς rhis "nose", ῥινός rhinos "of the nose", and the Latin vīrus) is the most common viral infectious agent in humans and is the predominant cause of the common cold.

Enterovirus

enterovirusesenteroviralenterovirus infections
Rhinoviruses belong to the genus Enterovirus in the family Picornaviridae.

Serotype

serovarserotypesserogroup
The three species of rhinovirus (A, B, and C) include around 160 recognized types of human rhinoviruses that differ according to their surface proteins (serotypes).

Lytic cycle

lyticlytic life cyclelytic stage
They are lytic in nature and are among the smallest viruses, with diameters of about 30 nanometers.

Smallpox

small poxvariolaVariola virus
By comparison, other viruses, such as smallpox and vaccinia, are around 10 times larger at about 300 nanometers; while flu viruses are around 80–120 nm.

Vaccinia

vaccinia virus Vaccinia virusE3L
By comparison, other viruses, such as smallpox and vaccinia, are around 10 times larger at about 300 nanometers; while flu viruses are around 80–120 nm.

Fomite

fomitescontaminated objectsobjects
There are two modes of transmission: via aerosols of respiratory droplets and from fomites (contaminated surfaces), including direct person-to-person contact.

Nasal congestion

nasal obstructioncongestionstuffy nose
Symptoms include sore throat, runny nose, nasal congestion, sneezing and cough; sometimes accompanied by muscle aches, fatigue, malaise, headache, muscle weakness, or loss of appetite.

Sneeze

sneezingAtchoo!Achoo
Symptoms include sore throat, runny nose, nasal congestion, sneezing and cough; sometimes accompanied by muscle aches, fatigue, malaise, headache, muscle weakness, or loss of appetite.

Cough

coughingdry coughproductive cough
Symptoms include sore throat, runny nose, nasal congestion, sneezing and cough; sometimes accompanied by muscle aches, fatigue, malaise, headache, muscle weakness, or loss of appetite.

Myalgia

muscle painmuscle achesmuscle pains
Symptoms include sore throat, runny nose, nasal congestion, sneezing and cough; sometimes accompanied by muscle aches, fatigue, malaise, headache, muscle weakness, or loss of appetite.